Women in IT Security, Women to watch

Critical Start’s Callie Guenther: Shaping the future of digital defense

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Cybersecurity isn't just a profession for Callie Guenther, but a mission that began in the U.S. Navy and continues at Critical Start, where she serves as a senior manager in cyber threat research.

Over the last year, Guenther has expanded the scope and effectiveness of Critical Start's All-Source Intelligence and Malware Reverse Engineering programs as head of its Cyber Research Unit (CRU). Under her leadership, the CRU established a robust intelligence pipeline by transforming data collection processes and the team has become a crucial part of the organization.

With a dedicated team focused on identifying and mitigating emerging threats and delivering invaluable insights to internal and external stakeholders, she has infused Critical Start’s programs with fresh insights and a data-driven mindset that have changed the way the organization — and the wider community — responds to emerging threats.

Her contributions haven’t stopped there. Guenther also leads the firm's advanced threat research initiatives, producing cutting-edge insights that solidify Critical Start’s reputation as an industry leader. Her efforts in expanding malware analysis and reverse engineering capabilities have led to faster mitigation of sophisticated threats. By championing intelligence-driven threat hunting protocols, Guenther has significantly reduced incident response times by identifying and neutralizing threats before they materialize.

One of her most innovative achievements has been the development of a dedicated threat hunting function, an initiative that required alignment across teams and the creation of cutting-edge methodologies. With Guenther's guidance, this function has evolved into a new revenue stream focused on threat intelligence, adding immense value for Critical Start’s Managed Detection and Response (MDR) customers and bolstering the company’s growth. Her leadership has ensured that Critical Start remains an industry frontrunner, equipped with the tools and insights needed to face tomorrow’s challenges head-on.

Beyond her technical achievements, Guenther has emerged as a respected voice within the broader cybersecurity community. Her insights are featured in SC Magazine’s "Perspectives" column, where she tackles some of the most pressing issues in the industry: ransomware attacks, data breaches, and the constant evolution of cyber threats.

Her columns not only guide other professionals but also offer a sense of clarity and perspective in a field that can often feel overwhelming. Guenther’s contributions underscore her commitment to knowledge-sharing, making her expertise accessible to those navigating the complex landscape of cybersecurity.

Guenther’s influence also reaches beyond her immediate work, particularly in promoting diversity within the field. Her journey is one of resilience and determination, beginning with her service in the Navy as an information systems technician, where she became the first enlisted person in the 7th Fleet to earn a warfare qualification in intelligence.

Her academic achievements — including advanced studies in government analytics and data science from Johns Hopkins University — have armed her with a unique perspective that continues to elevate her work and inspire those around her.

Whether she’s developing cutting-edge threat hunting methodologies, mentoring young professionals, or sharing her insights with the industry at large, Guenther is proving that cybersecurity is not just about defending against digital threats.

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